
It’s 2045; the Gene Revolution is changing humanity. The US has lost its technological crown, and the biotech capital of the world is now Singapore. In Change Agent, the techno-thriller by Daniel Suarez, the night is lit by bioluminescent trees, children play with neotenic pets, drug addicts enjoy custom highs, specialized for their individual DNA. International law prohibits human edits beyond those designed to correct a short UN-approved list of genetic diseases. But a few years after ratification, the UN Treaty on Genetic Modification is already a dead letter. Continue reading

Smoking is an addiction; tobacco, however, is a model plant full of virtues. Docile to biotech interventions, metabolically exuberant, able to churn out plenty of proteins. Now it has attracted 7.2 million euros through an EU research project aiming to harvest biopharmaceuticals by harnessing the power of photosynthesis and new plant breeding techniques.
Up and down, following the excitement for the latest scientific exploit or frustration for disappointing results. CRISPR is young but already knows how volatile is the market. “Preprint wipes millions off CRISPR companies’ stocks,” cries the March issue of
CRISPR needs to anchor itself near a short sequence called PAM to do its job. In the book “Modern Prometheus” (Cambridge University Press) James Kozubek says a PAM is like a shoehorn, where the Cas9 nuclease begins to clasp down to recognize the right site and cut. In order to fit every gene, a super-adjustable shoehorn would be needed. Think of it as the equivalent of a bump key that can open any door. A Broad Institute group led by David Liu has almost reached the goal with xCas9, the new super-adjustable Cas9 variant described in 
It is Science but it could be mistaken for The CRISPR Journal. The latest issue indeed runs three papers by three CRISPR aces – David Liu, Jennifer Doudna, and Feng Zhang – about the cutting-edge fields of
There is hardly any day without CRISPR news. February starts with researchers correcting abnormalities associated with Duchenne muscular dystrophy (