Editing the celiac diet. Is it GM bread?

gluten-free

Wheat contains many genes coding for proteins that are toxic to people with celiac disease (gliadins), but CRISPR could edit them all out. Researchers at the Institute for Sustainable Agriculture (Córdoba, Spain) have managed to knockout up to 35 of these genes, reducing immunoreactivity by up to 85%. The 100% goal now seems to be at hand. But is biotech “gluten-free” bread tasty? And is it going to reach the market? We asked plant scientist Francisco Barro, corresponding author of the paper recently published in Plant Biotechnology Journal. Continue reading

Debating the rules for CRISPR crops in Brussels

bruxelles cattura

The European Commission is organising the high-level conference “Modern Biotechnologies in Agriculture – Paving the way for responsible innovation”. This one-day event takes place in the Charlemagne Building today, from 9.30 to 18.00. The aim is to stimulate an informed and open debate among all stakeholders on how the EU can benefit from modern biotechnologies and innovation in the food and agricultural sector while maintaining high safety standards. The participants are prominent European policy makers, relevant industry stakeholders, representatives of civil society, scientists, and government experts. Webstreaming is available. For further information, see the conference website

 

Germany debates CRISPR

leopoldina

Germany stands out as the European country most interested in fostering an informed debate on CRISPR many uses. Today an interdisciplinary group of experts from the German National Academy of Sciences (Leopoldina) has published a Discussion Paper entitled “Ethical and legal assessment of genome editing in research on human cells”.  Experiments involving human embryos are prohibited by law in the country but the document suggests a possible compromise. Research should be permitted on “orphaned” embryos created for reproductive purposes but no longer going to be used for reproduction. In February the German academy co-organized a meeting on edited plants, discussing what kind of regulation would be suitable. In 2005 they published a statement on “The opportunities and limits of genome editing” and another one on molecular plant breeding. According to a Leopoldina official press-release, the annual assembly “will be intensively addressing the topic of genome editing” later this year.