
The destiny of new technologies greatly depends on their social acceptance. It makes sense, therefore, to try to understand whether the editing metaphor could make CRISPR appear more reassuring than other approaches to genetic modification. This idea has gained some ground and was discussed by several bioethicists in the American Journal of Bioethics. However, it is still an unproven hypothesis. A contribution to the debate comes from the journal Frontiers in Public Health, with a study suggesting that biotech metaphors have little impact on public perception. Continue reading

Perfection is not of this world, and no technology is perfect. But tolling the bell for CRISPR because of a single preliminary study last week was premature at best. Many voices are doubting the meaning of the Nature Methods paper reporting “hundreds of unintended mutations” putatively caused by genome editing. Some researchers have already announced that critical analyses and rebuttals are forthcoming. 
The aim is engaging: to treat an increasing number of diseases by correcting the underlying genetic defects. And researchers are breathing optimism at last. The San Raffaele Telethon Institute for Gene Therapy (
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