Heritable Editing: Yes or No?

According to the survey conducted by Pew Research Center in 20 countries, people are positive about gene-editing if used to treat illnesses a baby would have at birth (support is particularly strong in Spain). People are also generally in favor of using human gene editing to reduce the risk of future health problems, but less so. India is the only country where the majority says the possibility of using human gene editing to make a baby more intelligent is also acceptable. See more data here.

CRISPR news roundup

perv free piglets eGenesisIt’s mid-August, but CRISPR never goes on vacation. Not to be missed this week is the Science paper by George Church’s team. They have cloned 15 PERV-free piglets, meaning porcine retrovirus sequences have been edited out. The animals can now “serve as a foundation pig strain, which can be further engineered to provide safe and effective organ and tissue resources for xenotransplantation,” researchers write. According to the Harvard geneticist, the first pig-to-human transplants could occur within two years. Another article in the same journal feels the pulse of public perception of human genome editing, concluding that opinions are nuanced and the challenge is to find the best way to engage people in discussions about genome-editing regulation.

Engineering vs editing. What difference does it make to people?

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The destiny of new technologies greatly depends on their social acceptance. It makes sense, therefore, to try to understand whether the editing metaphor could make CRISPR appear more reassuring than other approaches to genetic modification. This idea has gained some ground and was discussed by several bioethicists in the American Journal of Bioethics. However, it is still an unproven hypothesis. A contribution to the debate comes from the journal Frontiers in Public Health, with a study suggesting that biotech metaphors have little impact on public perception. Continue reading