It’s mid-August, but CRISPR never goes on vacation. Not to be missed this week is the Science paper by George Church’s team. They have cloned 15 PERV-free piglets, meaning porcine retrovirus sequences have been edited out. The animals can now “serve as a foundation pig strain, which can be further engineered to provide safe and effective organ and tissue resources for xenotransplantation,” researchers write. According to the Harvard geneticist, the first pig-to-human transplants could occur within two years. Another article in the same journal feels the pulse of public perception of human genome editing, concluding that opinions are nuanced and the challenge is to find the best way to engage people in discussions about genome-editing regulation.