He’s version

He 5 core principles

Don’t miss the “Draft Ethical Principles for Therapeutic Assisted Reproductive Technologies” just published by He Jiankui et al. in The CRISPR Journal. It seems the Lulu and Nana’s experiment is at odds even with their own guidelines. We are eager to hear more from He’s voice, his talk in Hong Kong is scheduled on Wednesday, 28 November 2018 (Second International Summit on Human Genome Editing-live broadcast)

CRISPR rice vs GM rice: which would you buy?

Rice_grains_(IRRI)Just imagine you could find them all on the supermarket shelves, would you buy rice labeled as CRISPR or GMO, or stick to conventional non-genetically modified rice? And what price would you consider fair? Aaron Shew and colleagues from the University of Arkansas conducted a multi-country assessment of willingness-to-pay for and willingness-to-consume a hypothetical CRISPR-produced food and published their findings in Global Food Security. Continue reading

EU science advisors on CRISPR and GMOs

SAMThe European Commission’s Group of Chief Scientific Advisors has published a statement on gene editing and the GMO directive, following the controversial judgment released last July by the EU Court of Justice. They state that new scientific knowledge and recent technical developments made Directive 2001/18 “no longer fit for purpose.” Therefore “there is a need to improve EU GMO legislation to be clear, evidence-based, implementable, proportionate and flexible.” The document was welcomed by Carlos Moedas, Commissioner for Research, Science and Innovation, and Vytenis Andriukaitis, Commissioner for Health and Food Safety. Let’s hope actions will follow, and laws keep up with labs.

CRISPR meets machine learning

If a donor template is not provided when CRISPR cuts the DNA, broken ends are fixed by natural repairing mechanisms in a way that is considered stochastic and heterogeneous. This makes template-free editing impractical beyond gene disruption, right? Wrong, according to a study published in Nature by Richard Sherwood and colleagues. Continue reading

CRISPR, that old dress and what Art is

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BioArt is entering the genome-editing era. The first CRISPR artwork is a World War II dress, patched with silk and bacteria by British bioartist Anna Dumitriu. You can read more about its science and meaning in the CRISPR Journal and Labiotech. But where does the dress come from? And if this is art indeed, what about the galloping horse CRISPRed by George Church last year? I asked Dumitriu, please find the answers below.  Continue reading

The Netherlands are calling. Will the EU answer?

windmillA proposal from the Netherlands Ministry of Infrastructure and the Environment points the way out of the GM regulatory impasse for most CRISPR crops in Europe. Rather than trying to clarify ambiguous definitions, the EU could simply amend Annex B1, that is the list of technologies that are excluded from regulation by the directive on GMOs (2001/18/EC). Continue reading