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About Anna Meldolesi

science writer

The latest twist in the battle to control CRISPR

Credit: Cal Alumni Association

Emmanuelle Charpentier and Jennifer Doudna won the Nobel Prize but not the intellectual property dispute and are now ready to give up two patents granted in Europe. The scoop once again comes from Antonio Regalado, who gained fame a few years ago for breaking the CRISPR babies scandal.

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MicroRNAs and the traffic flow in Manhattan

MicroRNAs won Victor Ambros and Gary Ruvkun the 2024 Nobel Prize in Medicine. Thomas Cech (Nobel Laureate for the discovery of catalytic RNA) has found a fun way to explain how they work. His book, which I reviewed a few weeks ago, is a mine of insights and information. Here is a small excerpt.

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CRISPR vines make their field debut in Italy

Testing of Chardonnay edited to resist downy mildew starts today near Verona, while the prosecco variety awaits its turn in the greenhouse

The president of the influential farmers’ association Coldiretti, Ettore Prandini, formerly very hostile to GMOs, as he plants an edited vine with his own hands in the Verona experimental field on Sept. 30, 24
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CRISPRing at school – for 2$

Forget Odin, the controversial kit that was being sold online by controversial “biohacker” Josiah Zayner (getting people to play around with developing antibiotic-resistant bacteria is certainly not a good idea). At Stanford University they have developed a CRISPRkit for cell-free in vitro experiments that is easy and safe because the target is a harmless pigment. And the great thing is that it costs less than an American coffee (two dollars).

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Never underestimate RNA or lowly creatures

RNA interference, mRNA vaccines, RNA-guided editing. These are just some of the fields of biomedical research that have exploded in recent years and brought RNA out of the projected shadow of the most famous nucleic acid: DNA. Credit for the ongoing scientific and technological revolution goes to researchers such as Thomas Cech, who have been able to look beyond the double helix and, in many cases, have earned Nobel prizes (the latest being Katalin Karikό for the anti-Covid vaccine). But we also owe a nice gratitude to the strange critters who first exhibited some unexpected phenomena that later became of universal interest.  

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Where ag genetics goes (in Italy and beyond)

Four intense days of talks and discussions on the present and future of agricultural genetics. We will be there at the round table “Social impact of plant biotechnologies: challenges and opportunities” (12 September afternoon). See the full program here.