CRISPR in Trump’s time

A wait-and-see atmosphere lingers in the biotech and pharma sector. Vice President-designate J.D. Vance recently spoke with enthusiasm on Joe Rogan’s podcast about the first CRISPR treatment to hit the market—the one for sickle cell anemia. However, there’s rising concern about RFK Jr., who could exert significant influence over health and food policies. His broad “natural = good” ideology is both philosophically and scientifically dubious, and his clear anti-GMO positions are worrisome. Listening to his conversation with anti-biotech activist Jeffrey Smith on the RFK Jr. podcast reveals a revival of the classic 1990s narrative—corporations as villains, a corrupt establishment, suppressed scientists, concealed health risks—all now repurposed to criticize CRISPR technology, which is portrayed as unreliable and uncontrollable.

MetaCRISPR, how to edit microbiomes

Jill Banfield and Jennifer Doudna (photo by Keegan Houser)

The best way to summarize the new metaCRISPR approach, recently published in Nature Microbiology, is the Twitter thread by Jill Banfield:

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CRISPR children, how are they?

Credit: Stefano Navarrini, Innovative Genomics Institute, Anna Meldolesi

Lulu and Nana are three years old. Amy is the name Nature Biotechnology uses to refer to the third CRISPR baby, born in late spring-early summer 2019. Their health is a closely held secret, that Vivien Marx has investigated for the journal’s December issue. “A full understanding of the health risks faced by the children due to their edited genomes may lie beyond the reach of current technology”, she writes. Despite or maybe because of that, the news feature is well worth reading. Below are a few points:

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