Merry CRISPmas from CRISPeR Frenzy!
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Category Archives: Crazy4Crispr
The Nobel Lectures and CRISPR Casɸ
Here you can watch le Nobel Lectures by Emmanuelle Charpentier and Jennifer Doudna. Emmanuelle is very focused and très, très chic, oui. Jennifer is generous with credits to colleagues and willing to represent the public conscience of genomic editing. The thing I liked most is the reference to CRISPR-Casɸ: a hypercompact genome editor found in huge phages. Probably it evolved to target the genes of competing phages inside bacterial hosts.
Continue readingIt’s Nobel Week, let’s party
Traditionally the Nobel Laureates travel to Stockholm to receive their prizes. This year the prizes are coming to them. On 7 December, 19.00 CET, the diploma and medal will be presented to Emmanuelle Charpentier at the Swedish Ambassador’s Residence in Berlin. On 8 December, 16.00 PST, it’s Jennifer Doudna’s turn at the Residence of Barbro Osher, Honorary Consul General in San Francisco. Also on 8 December, 11-13 CET, we can watch online the Academy’s official Nobel Lectures 2020: For the development of a method for genome editing, by Emmanuelle Charpentier, and The Chemistry of CRISPR: Editing the Code of Life, by Jennifer A. Doudna. Full programme here.
CRISPR rising stars
December is time for rankings and forecasts. Let’s start with STAT News celebrating young talents who could become the next generation of scientific superstars. Three CRISPR researchers appear among STAT wunderkinds. As a postdoc at the Broad Institute, Andrew Anzalone helped make a key advance by developing prime editing, where the same RNA molecule specifies the target and the desired edit. Jennifer Hamilton, from Berkeley, works on solving one of the major hurdles of CRISPR-based therapies: delivering the genome editor to the desired cells. Cameron Myhrvold, has since worked at the Broad Institute on developing CRISPR-based diagnostics such as CARMEN and is about to start his own lab at Princeton.
CRISPR goes graphic
No wonder “Editing Humanity” by Kevin Davies is good reading. The executive editor of The CRISPR Journal (and the founding editor of Nature Genetics) is really in a great position to tell the CRISPR story so far. But the book deserves praise also for its aesthetic qualities, i.e., pictures and graphics. I’m totally in love with the typographical character marking the start of paragraphs – there is a sign representing Cas9 in place of the conventional pilcrow ¶.
Crisp & malty. Your first CRISPR beer
This is probably the first product branded as CRISPR-edited, how cool is it? The science comes from Berkeley Yeast. The cans are sold by Temescal Brewing and the claim is “Crisp, Malty, Helles Lager”.
Continue readingIt’s CRISPR Nobel!
Where is the revived mammoth?
I watched Genesis 2.0, which is debuting in Italy almost two years after its release at the Sundance Film Festival. In the meanwhile, Semyon Grigoriyev has died. The Russian paleontologist leading the effort to clone a mammoth was one of the movie’s main characters. He always had little chance of success, and the plan’s odds are now worse than ever.
Continue readingDoudna’s evil twin on Netflix
I watched the first season of Biohackers, the new Netflix tech thriller. I will try to limit spoilers as much as possible. What interests me now are the characters: what do they tell us about CRISPR perception? Are they original or stereotypical?
Continue readingCRISPR & society, the dialogue resumes
