All-male mosquitoes to beat malaria

Anopheles gambiae (credit Alekos Simoni)

The idea is bold and seems to have worked fine. By using a DNA cutting enzyme to disrupt the X chromosome, researchers succeeded in distorting the sex ratio of offsprings, eventually leading to the all-male populations collapse. Andrea’s Crisanti and colleagues at the Imperial College London did it to caged Anopheles gambiae mosquitoes in their quest for a genetic strategy to beat malaria. Please see their paper in Nature Biotechnology and the Imperial College press release.

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