Tag Archives: NGTs

My journey to Seville, where tomorrow’s sunflowers grow

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Anyone who has ever stood beside a sunflower knows the quiet astonishment of being matched, petal for head, by a flower. Now imagine weaving your way through tens of thousands of stems at eye level, each one tethered to the transparent ceiling by a white cord, as if suspended between earth and sky. Overhead stretches a vision in perfect symmetry: thousands of threads rising in parallel, anchoring a forest of blossoms veiled like brides at the altar, their vivid yellow only just shimmering through the gauze. It could be a contemporary art installation, but this is the greenhouse of the world’s most advanced sunflower research center. We are not at the Venice Biennale nor at Documenta in Kassel, but just outside Seville, at the Centro Tecnológico de Investigación de La Rinconada.

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Italian Food for Thought

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Food for Thought is a coalition of 18 Italian associations in the agrifood sector, established in 2017 to promote innovation in agriculture. Today, nearly eight years after the first manifesto, a new one has been presented to address the challenges of both the present and the future, including the climate crisis, geopolitical tensions, and changing consumption patterns.
The event was held yesterday in Rome at the initiative of Senator Bartolomeo Amidei, as part of the activities of the Parliamentary Intergroup on Made in Italy and Innovation.
Among the key points is the inclusion of New Genomic Techniques — a clear sign that there is widespread awareness within the Italian productive sector of the importance of genetic improvement, and that there are voices in the national Parliament willing to advocate for “innovative and sustainable agriculture.”

Will edited plants be patentable in EU?

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A year after the European Parliament voted to ban patents, EU countries still seek a compromise on NGT regulation

The revision of the regulatory framework for genetically modified plants currently underway in Europe aims to keep pace with technological advances and support the development of sustainable agriculture. The scientific community, the seed industry, and major farmers’ associations view the overall framework positively, but the devil is still in the details.

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Fall and Rise: Italy’s Journey from GMOs to CRISPR

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Italy has long been one of the most hostile countries toward GMOs, to the point of shutting down research in this field. Today, however, it stands among the most active EU members in testing New Genomic Techniques. How did this transformation happen? EMBO Reports features insights from some of the Italian scientists who have championed the defense of GMOs and the revival of experimental fields. Happy reading!

CRISPR vines make their field debut in Italy

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Testing of Chardonnay edited to resist downy mildew starts today near Verona, while the prosecco variety awaits its turn in the greenhouse

The president of the influential farmers’ association Coldiretti, Ettore Prandini, formerly very hostile to GMOs, as he plants an edited vine with his own hands in the Verona experimental field on Sept. 30, 24
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Will edited foods appeal to consumers?

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While the number of studies on this topic is limited, they generally align in indicating that genome-edited plants are more appealing to the public than GMOs. Supporting this assertion is an analysis set to be published in the June issue of Current Opinion in Biotechnology. Hans De Steur and his colleagues at the University of Ghent in Belgium conducted a review of data collected from various countries worldwide, including Europe, Asia, and the Americas.

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CRISPR plants – what the EU Parliament got right and wrong

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There is no doubt that this is good news: on February 7, the European Parliament approved the Commission’s regulatory proposal on New Genomic Techniques, covering also CRISPR plants. Some of the approved amendments (particularly the one on genetic modification of polyploid plants) have the effect of improving the text, others risk being a problem and should be reconsidered during the trilogue with member states (particularly the requirement to label all final products, even if they do not contain foreign genes). The European Parliament also brought in the issue of non-patentability of NGT plants, which would deserve to be addressed elsewhere. For more information, this is the position expressed on February 14 by European Plant Science Organisation (EPSO).

A multiple sclerosis trial and more CRISPR news

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Anyone interested in advanced therapies is familiar with the acronym CAR-T. These are T lymphocytes modified (also with the help of CRISPR) to better recognize and attack cancer cells, and they have already proven to be a successful strategy for blood tumors. Now hopes are high that a similar approach may also prove useful for multiple sclerosis, which is an autoimmune disease. The idea is to use CAR-Ts to prevent B lymphocytes from attacking nerve cells, including in the brain. The first clinical trial is recruiting patients in the U.S. Read more in Nature.

Let’s come to the use of New Genomic Techniques in crops. The European Commission’s regulatory proposal (approved by the EU Parliament on Feb. 7) excludes the use of edited plants in organic farming, but among organic producers not everyone is against NGTs and this may bode well for a possible peaceful coexistence between the different types of production in the years to come.

Finally, we point out the latest advance in animal editing: porcine virus-resistant pigs. The paper came out in the CRISPR Journal, but you can also read about it in GEN.

CRISPR crops – Italy fires the starting gun

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A CRISPR/Cas9-modified rice variety may be planted in a test field in northern Italy as soon as this spring after a government rule change introduced in 2023. A University of Milan team was the first research group in the country to apply for a field test under a law change that streamlines procedures for field trials of plants developed through genome editing or cisgenesis. With several other groups also planning proposals, a new wave of agricultural genetics in Italy could follow. [Please see the details in my article for Nature Italy]

A brief guide to the messy Italian debate on NGTs

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There is great disorder under the heavens of new biotechnology. Judging by the Italian debate on genetic innovation in agriculture, it seems that we no longer know what to call what. We are waiting for the European Commission to present its proposal to regulate ‘new genomic techniques’ (NGTs) on 5 July (see the leaked draft here). But in the meantime, on 9 June, the Italian Parliament approved a regulation in favour of experimentation with ‘assisted evolution techniques’ (TEAs), which are the same thing. However, if you read the official wording (9 bis, drought decree law) this expression is missing: instead, it refers to the deliberate release into the environment for experimental purposes of ‘organisms produced by genome editing techniques through site-directed mutagenesis or by cisgenesis’.

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