CRISPR at its hottest

Source AddGene blog

The picture shows a moment in the sample-collecting effort leading to this Pnas paper about a novel heat-tolerant CRISPR enzyme called IgnaviCas9. Exploring nature’s molecular diversity in extreme environmental conditions such as Yellowstone hot springs can yield exciting discoveries and applications.

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The CRISPR world we live in

crispr distribution

“As of January 2018 Addgene has distributed more than 100,000 CRISPR plasmids to 3,400 laboratories worldwide. More than 6,300 CRISPR-related plasmids have been developed by over 330 academic labs and deposited into Addgene’s collection. Geographically, new CRISPR plasmids have been developed and deposited to Addgene’s collection from the Americas (led by the United States), Europe (led by Denmark), Asia (led by China), and Oceania (led by Australia), and shipped to some 75 countries.” [Reference: Enabling the Rise of a CRISPR World, Caroline M. LaManna and Rodolphe Barrangou, The CRISPR Journal, Vol. 1, n. 3, 2018]