About Anna Meldolesi

science writer

CRISPR best and worst in 2018

CRISPR contributed to Science’s Breakthrough of the Year and was also nominated for the Breakdown category by the same journal. The second nomination was an easy guess: He Jiankui and its baby-editing claim were also mentioned in Nature’s 10 for 2018. Much more interesting is the decision to celebrate cell-barcoding, the CRISPR-based technique used to track embryo development in stunning detail and over time. Continue reading

CRISPR babies, not so breaking news?

nyt front page news

Never at the top of front pages (Nyt, 27 Nov. 2018)

Twenty days after the announcement, many questions remain. The one certainty seems to be that the first  CRISPR babies are less breaking news than expected.

They will be in front pages again, probably, if and when the scientific paper gets published, if and when the baby-editor He Jiankui resurfaces, if and when the first photos of Lulu and Nana are circulated. But if the coverage of Dolly the sheep is considered in comparison, there’s no match. Why?

The media world has changed dramatically in the meantime, CRISPR is still unknown to many, China is perceived as a Wild East where anything can happen. But a sheep is always a sheep, and babies are babies. We should care about the first edited kids more than that. Maybe people are less troubled by human genome editing than most bioethicists. Perhaps the media have had enough of Gattaca, Frankenstein, and the likes. Did we cry wolf too often yesterday to get people interested today?

CRISPR seeds: the asexual revolution is now

apomictic rice UC Davis

Imtiyaz Khanday (left), Venkatesan Sundaresan (right)  with their apomictic rice  (credit: KARIN HIGGINS/UC DAVIS)

“To make a seed it takes a fruit,” pupils use to sing in Italy. Then students learn that there is an embryo inside seeds and it takes a pollen fertilized egg to make it. The dream of plant scientists, however, has always been to be able to produce seeds using only the cell egg. This dream has finally come true: a group led by Venkatesan Sundaresan, at UC Davis, has developed a rice variety capable of cloning its seed. Continue reading

Milan toasts with biotech wine

aperitivo biotech 2

Assobiotec tasting event in Milan (photo credit: Marco Marazza)

When toasting during Christmas holidays, perhaps with a glass of Italian sparkling prosecco, think about it: viticulture in Europe occupies 3% of the cultivated area, but it accounts for 65% of all fungicides employed in agriculture. The adoption of new wine grape varieties resistant to powdery and downy mildew could significantly cut chemical use. If fairly regulated, advanced biotech tools such as CRISPR could help sustainability without losing anything of the genetic identity of iconic varieties. Continue reading

He’s version

He 5 core principles

Don’t miss the “Draft Ethical Principles for Therapeutic Assisted Reproductive Technologies” just published by He Jiankui et al. in The CRISPR Journal. It seems the Lulu and Nana’s experiment is at odds even with their own guidelines. We are eager to hear more from He’s voice, his talk in Hong Kong is scheduled on Wednesday, 28 November 2018 (Second International Summit on Human Genome Editing-live broadcast)

CRISPR rice vs GM rice: which would you buy?

Rice_grains_(IRRI)Just imagine you could find them all on the supermarket shelves, would you buy rice labeled as CRISPR or GMO, or stick to conventional non-genetically modified rice? And what price would you consider fair? Aaron Shew and colleagues from the University of Arkansas conducted a multi-country assessment of willingness-to-pay for and willingness-to-consume a hypothetical CRISPR-produced food and published their findings in Global Food Security. Continue reading