A new atlas for plant genomes

As we become increasingly able to reshape genomes, the need to organize information in efficient and accessible ways continues to grow. More than a thousand plant genomes have now been sequenced, with the pace accelerating, so it is good news that the plant genetics community can rely on PubPlant, a new interactive, updatable, and freely accessible atlas introduced in Frontiers in Plant Science. The magazine The Scientist has written about it, likening PubPlant to a kind of Google Maps for plant DNA, designed to help researchers more quickly pinpoint key genomic regions linked to traits such as disease resistance, nutritional quality, or climate adaptation. (Image Credit: Salk Institute-USDA)

CRISPR patents by numbers

CRISPR patent landscape IPStudies
Number of applications for new patent families filed worldwide. Data from 2018 and 2019 are incomplete. Due to a lag in the publication of US filings, most of the applications included in the tally are in China. [Credit IPStudies/The Scientist]

According to IPStudies, over 12,000 CRISPR patent applications have been filed worldwide, falling into about 4,600 patent familiesThe number of issued patents is still impressive, more than 740 to date. More than half have been awarded in just two countries. Can you guess where?

China and the US, of course. Players dominating the patent landscape are the University of California and the Broad Institute – where CRISPR was respectively invented and adapted for genome editing in eukaryotes – the Chinese Academy of Sciences, the US company DuPont and the Massachusetts-based biotech firm Editas Medicine.

The struggle between UC and Broad over the standard Cas9 system is still on and is pushing the development of alternatives. CRISPR enzymes now come in approximately 50 different types, including Cpf1, C2c2,  and CasY.

The partial score at the US and the EU patent offices is 34 patents granted to the Boston team and 10 to Berkeley. To learn more, read The Scientist.