I want to highlight a lecture recently given by one of the most influential scientists in the international debate on GMOs and gene editing in agriculture. Born in India, C. S. Prakash lives and works in the U.S. and has been elected a fellow of the American Association for the Advancement of Science (AAAS). His lecture, delivered at the AAAS Center for Scientific Evidence in Public Issues, traces the progress made over the past sixty years in the field of global food security—i.e., meeting the growing demand for food from the world’s population.